Pomalidomide-C3-NH2 hydrochloride( —— )

Catalog No. M28255 CAS No. 2154342-45-5

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Datasheet

HNMR

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Product Name

Pomalidomide-C3-NH2 hydrochloride
Note

Research use only, not for human use.
Brief Description

Pomalidomide-C3-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based CRBN ligand and linker used in PROTAC technology.
Description

Pomalidomide-C3-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based CRBN ligand and linker used in PROTAC technology.
In Vitro

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
In Vivo

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Synonyms

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Pathway

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Target

Other Targets
Recptor

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Research Area

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Indication

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1.Chen S, et, al. A new diterpenoid alkaloid 8-deacetylyunaconitine from the roots of Aconitum forrestii. Yunnan Zhiwu Yanjiu. 1984; 6(3):338-40.

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